The Photographer's Guide to Los Santos blends video games and photography, exploring Grand Theft Auto V as both a tourist destination and a creative space. Combining practical in-game photography advice with critical analysis, the guide offers tutorials, modding techniques, and reflections on artistic projects, making it a valuable resource for students and digital artists. This handbook redefines GTA V as a medium for artistic expression, challenging conventional boundaries between gaming and art. Drawing from exhibitions and in-game performances, the guide incorporates lessons from teaching in-game photography across Europe. The Photographer's Guide to Los Santos encourages deep, creative engagement with GTA V, positioning the game as a site for both critical and artistic exploration.