This book of exercises in Machine Learning is the product of eight years of experience in teaching exercise classes at Politecnico di Milano. It is designed to be a comprehensive and practical resour- ce for a diverse audience, including students and professionals seeking to enhance their skills in this rapidly evolving field. The structure of the book is organized into chapters, each focusing on a specific topic. At the beginning of each chapter, the reader will find a Practical Session that introduces the key concepts relevant to the topic and complements them with code examples in Python. Each exercise comes with a detailed solution that guides the reader through the process and methodology behind it.