The book "European Structural Funds 2021-2027" is characterized by a decidedly innovative approach and is aimed at businesses, training companies, freelancers, public sector employees, Universities, and the political world. The Author pays greater attention to practical activities such as project design and expense reporting, which must be well understood by those who intend to access European funds. The new European Regulations relating to common provisions, the European Regional Development Fund (ERDF), and the European Social Fund Plus (ESF+) are explained starting from the new elements compared to the previous period. The strategic policy objectives (POs), the different classification of regions, the new architecture of the Management and Control Systems (MCSs) are the central topics of the book and provide an overview of the 2021-2027 programming. The book guides the reader in drafting a European project, illustrating the main phases with reference to the two most important design tools recommended by the European Commission in its calls for proposals: the Logical Framework Matrix and the Project Cycle Method.