Today we think of public health as "the science and art of preventing disease, prolonging life and promoting he-alth", but how was this concept shaped? Through a story made of words and images, these pages reconstruct the historical roots of health and the path that from the early modem age led it to become public, in an intertwining of medicine and administration, science and control. Between the late 15th and 18th centuries, health practices hifted from being a run-up to face frequent epidemie th-eats to an activity of planning and prevention. Since medicine was stili very uncertain and ineffective at the time, the success of early modem age health measures resulted from an efficient administration and a widespread control of information. To study this evolution, the volume focu-ses on the Northern Adriatic: here, in fact, the first quarantine protocols, the first lazarets, the first permanent health magistracies were established. The focus is on the 18th century, because in this period health practices became more and more systematic and widespread . What emerges in the end is how Venice, in collaboration and competition with other Mediterranean port cities, invented public health.