In this book are analyzed topics related to COVID-19 which form the basis of the understanding of the multiple aspects related to the protection of public health, and which will allow the reader to broaden his or her understanding of how the system of preparation for the global pandemic is developed. Today, on the eve of the first fifth of the twenty-first century, we have new tools which allow us the management of pandemics. Will be described what are those tools, deepening several topics which are interrelated and which create the healthcare system. The book focuses in particular on the management of clinical studies, the pharmaceutical patent system, gene sequencing and the role of artificial intelligence in the protection of public health and fundamental human rights, observing how all this different tools are used to address the COVID-19.